3T Research Facilities

              A Philips Achieva 3T MR system equipped with Philips' SENSE accelerated imaging hardware and software as well as a multitude of image acquisition sequences is fully dedicated to research and available on campus. The system features sixteen RF receiver channels and a high performance gradient system ("Quasar Dual High Performance Gradient System") capable of on axis (x, y and z) 80 mT/m peak and 200 mT/m/ms slew rate. The system is also equipped with high linearity actively shielded gradient coil designed to be force balanced at 3.0T to minimize eddy currents and acoustic noise along with a state-of-the-art water-cooled gradient amplifier technology combined with a non-resonant coil design. The system features a 60-cm patient bore diameter and a fully automatic high order shimming (up to 2nd order) to ensure excellent image quality over a 40-cm imaging FOV. The system also provides a >1200 images per second reconstruction speed and supports DICOM, NIfTI-1, and Philips' PAR/REC image formats. Currently available RF coils include T/R Body, T/R Head, 8 channel SENSE Head, CTL Spine, 6 channel SENSE Cardiac, and 6 channel SENSE Torso. The system is housed at the Center for Functional Onco-Imaging (CFOI) and currently used for human research studies such as fMRI and diffusion tensor imaging (selectable up to 128 directions).

    4T/94-CM BORE MR SYSTEM

              A Philips 4 Tesla whole body MR system is available at the center for human and animal studies. The 4T whole body magnet (Magnex Scientific Inc.) with a clear bore of 940 mm is interfaced with a Marconi Medical Systems EDGE console for the pulse sequence generation and data acquisition. This system in narrow band mode operates at 170MHz. It uses a 12 KW CPC (Model 4T12K) RF amplifier that has a frequency range of 160-180 MHz. For spatial encoding, a whole body gradient coil built by Tesla is used. The coil is actively shielded and water-cooled also includes a 13-channel shim set. When it is used with a gradient amplifier system from MTS QDCM 950/200/4400, it generates fields up to 30 mT/m with a slew rate of 115 T/meters/second at 950 Volts/440 Amperes. The large bore size of the system enables us to integrate various other imaging instrumentations into the bore thus making it possible to pursue multi-modality imaging. The system has various pulse sequences for different imaging needs. Rapid sequences like Echo Planar Imaging (EPI), Fast Spin Echo (FSE), and Spoiled Gradient Recalled Acquisition at Steady State (SPGR) are available. The system is also interfaced to an ISOL console (Model ISOL ISP-400) for multinuclear applications. The ISOL spectrometer has 12 receiver channels with 8 channels dedicated for H-1 MR while one channel each for Na-23, P-31, F-19, and C-13. For multinuclear applications we also have a 4 KW CPC (Model 5T4KS) RF amplifier with a frequency range of 20-210 MHz. Various home-built RF coils including multi-frequency small animal birdcage, and surface coils are available.

    7T/15-CM BORE MR SYSTEM

              This system uses an Oxford 300/150 horizontal magnet with an inner bore size of 150 mm. The magnet is interfaced to an upgraded SMIS broadband console (MR Research Systems MR3330) for multi-nuclear applications. There is a Resonance Research actively shielded and water cooled gradient coil (Model BFG-150/90-S) with a gradient strength of 300 mT/m, a 100 ?sec rise time, and an inner diameter of 90 mm. The gradient coil also has a 13-channel built-in shim set. The system employs up to 2 Techron 7700 gradient amplifiers per axis and a Dressler 400-watt RF amplifier with a bandwidth 30-305 MHz (Model LPPA 3004). Various small animal RF coils including birdcage, surface, and dual resonance coils have been built in-house for research studies. Additionally various electronic circuitry has also been built for physiological gating during image acquisition. GE NXI ADVANCE WHOLE BODY PET SYSTEM The PET system is available for human and animal studies. It is a state-of-the-art positron emission tomography scanner, optimized for clinical studies but powerful and flexible enough for a wide range of research applications, with particularly strong capabilities in oncology and neuroscience.